HIV-1 variants in South and South-East Asia.
Int J STD AIDS
; 6(2): 117-20, 1995.
Article
em En
| MEDLINE
| ID: mdl-7779924
ABSTRACT
HIV spread in South and South-East Asia is most alarming, and genetic variability of HIV-1 is an important consideration in vaccine development. In this study, we examined the third variable (V3) region of env gene of HIV-1 variants prevalent in Thailand, Malaysia, India, and the Philippines. By phylogenetic tree analyses, an HIV-1 variant from an injecting drug user (IDU) in Thailand belonged to subtype B, and HIV-1 variants from 2 IDUs in Malaysia were classified into 2 subtypes, B and E. One HIV-1 variant from a male homosexual in the Philippines belonged to subtype B. Out of 8 HIV-1 variants from sexually transmitted disease patients in India, 7 belonged to subtype C, and one to subtype A. Although the total number of individuals examined in this study was limited, 4 HIV-1 subtypes were found in South and South-East Asia and large international movements of HIV-1-infected individuals in this region could induce global dissemination of these HIV-1 variants.
Palavras-chave
Asia; Behavior; Developing Countries; Diseases; Drug Usage; Examinations And Diagnoses; Genetic Technics; Heterosexuals; Hiv; Hiv Infections; Hiv Serodiagnosis; Homosexuals; India; Iv Drug Users; Laboratory Examinations And Diagnoses; Malaysia; Philippines; Research Report; Sex Behavior; Southeastern Asia; Southern Asia; Thailand; Viral Diseases
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Infecções por HIV
/
HIV-1
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Int J STD AIDS
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Japão