[During the treatment or after... drug-induced convulsive accidents. Apropos of 70 cases]. / En cours de traitement ou à l'arrêt ... les accidents convulsifs liés aux médicaments. A propos de 70 observations.
Therapie
; 49(5): 439-42, 1994.
Article
em Fr
| MEDLINE
| ID: mdl-7855760
ABSTRACT
During a five year period (1988-1992) 70 cases of seizures were collected by the Adverse Drug Reaction Monitoring Center of Clermont-Ferrand (3.58% of total collected cases). 31 cases (22 M and 9 F) occurred after a drug withdrawal. Benzodiazepines--either alone or in association--were the most often involved. Mean age was 48.8 +/- 2.6 years in this group and additional factors (alcohol abuse and/or association of drugs that lower the seizure threshold) were associated in 26 cases. 39 cases (14 M and 25 F) occurred on the course of various treatments. The most frequently involved drugs were neuropsychiatric, antiinfectious (especially beta-lactam antibiotics, fluorquinolones and isoniazid) and theophylline. Mean age was 56.5 +/- 3.8 years and additional different factors (high dosages, antecedents of epilepsy, underlying diseases) were present in 22 observations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Convulsões
/
Síndrome de Abstinência a Substâncias
Tipo de estudo:
Etiology_studies
Limite:
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
Fr
Revista:
Therapie
Ano de publicação:
1994
Tipo de documento:
Article