TAME-esterase activity during a prolonged attack of asthma.

ABSTRACT

We measured serum N-alpha-tosyl-L-arginine methyl ester (TAME)-esterase activity in a group of patients suffering from a prolonged attack of asthma. Measurements were made pre and post salbutamol nebulization. Our results showed that TAME-esterase activity did not change significantly pre or post nebulization. Based on our experimental data, we concluded that increase serum TAME-esterase activity is a biochemical substance associated with the early asthmatic response but not with prolonged attack of asthma.