Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding.
J Trauma
; 37(4): 607-15, 1994 Oct.
Article
em En
| MEDLINE
| ID: mdl-7932892
ABSTRACT
In this multicenter prospective controlled trial, 98 evaluable patients sustaining major torso trauma were randomized to receive early enteral nutrition with a new "immune-enhancing" diet (study n = 51) or a standard stress enteral formula (control n = 47). At baseline, both groups had comparable demographics and Injury Severity Scores. After 7 days of feeding, the groups had equivalent increases in serum total protein, albumin, and transferrin concentrations. Patients receiving the "immune-enhancing" diet, however, experienced significantly greater increases in total lymphocyte (p = 0.014), T lymphocyte (p = 0.04), and T-helper (p = 0.004) cell numbers. Additionally, these patients had significantly fewer intraabdominal abscesses (study, 0% vs. control, 11%; p = 0.023) and significantly less multiple organ failure (study, 0% vs. control, 11%; p = 0.023). In conclusion, this multicenter trial suggests this "immune-enhancing" enteral diet offers clinical benefits in stressed surgical patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traumatismos Torácicos
/
Nutrição Enteral
/
Traumatismos Abdominais
/
Sistema Imunitário
Tipo de estudo:
Clinical_trials
/
Observational_studies
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Trauma
Ano de publicação:
1994
Tipo de documento:
Article