Developmental changes in cardiorespiratory patterns of sleep-associated apnea in northern elephant seals.
Am J Physiol
; 267(5 Pt 2): R1294-301, 1994 Nov.
Article
em En
| MEDLINE
| ID: mdl-7977857
ABSTRACT
The development of heart rate and respiratory patterns related to sleep-associated apnea were studied in northern elephant seal (Mirounga angustirostris) pups and adult males. Heart rate patterns became more refined in conjunction with an age-related increase in apnea duration in pups. That is, older pups showed significant sinus arrhythmia, while breathing and apneic heart rate were both stable and similar in magnitude to the sinus arrhythmia minimum. By contrast, younger pups showed poor or nonexistent sinus arrhythmia and shorter apnea durations with a variable and/or high heart rate during apnea. Apnea duration was positively correlated with the development of sinus arrhythmia and negatively correlated with both eupneic and apneic heart rate. Adult males showed extremely well-developed patterns of sinus arrhythmia and, in all cases, the minimum heart rate during the sinus arrhythmia was lower than the average heart rate recorded during apnea. These results suggest that seal pups are not born with the cardiac control associated with voluntary long duration apnea, but that apnea tolerance increases with refined cardiorespiratory control.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Respiração
/
Síndromes da Apneia do Sono
/
Envelhecimento
/
Focas Verdadeiras
/
Eletrocardiografia
/
Frequência Cardíaca
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
Am J Physiol
Ano de publicação:
1994
Tipo de documento:
Article