Alcoholic dementia.
Can J Neurol Sci
; 21(2): 88-99, 1994 May.
Article
em En
| MEDLINE
| ID: mdl-8087744
ABSTRACT
At least four distinct cerebral diseases--Wernicke-Korsakoff, Marchiafava-Bignami, pellagrous encephalopathy, and acquired hepatocerebral degeneration--have a close association with chronic alcoholism. Each is characterized by a distinctive pathologic change and a reasonably well-established pathogenesis; in each the role of alcohol in the causation is secondary. The question posed in this review is whether there is, in addition to the established types of dementia associated with alcoholism, a persistent dementia attributable to the direct toxic effects of alcohol on the brain--i.e., a primary alcoholic dementia. The clinical, psychologic, radiologic, and pathologic evidence bearing on this question is critically reviewed. None of the evidence permits the clear delineation of such an entity. The most serious flaw in the argument for a primary alcoholic dementia is that it lacks a distinctive, well-defined pathology, and it must remain ambiguous until such time as its morphologic basis is established.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicoses Alcoólicas
/
Encéfalo
/
Transtorno Amnésico Alcoólico
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Can J Neurol Sci
Ano de publicação:
1994
Tipo de documento:
Article