Late-onset, seropositive, erosive rheumatoid arthritis.
Semin Arthritis Rheum
; 23(3): 177-82, 1993 Dec.
Article
em En
| MEDLINE
| ID: mdl-8122120
ABSTRACT
This report describes the natural history, clinical features, and therapeutic requirements of late-onset seropositive and/or erosive rheumatoid arthritis (LORA). One hundred twenty-nine patients with mean disease duration of 6 years and mean age of disease onset of 66 years were studied. All patients met American Rheumatism Association criteria for rheumatoid arthritis (RA). Ninety-one percent were seropositive for rheumatoid factor, 83% had erosive disease, and 58% had significant medical problems. Therapeutically, most patients required sequential use of multiple second-line agents. Functional classification did not change significantly despite treatment, and complete remissions were unusual even with remittive therapy. It is concluded that a subset of LORA patients have seropositive aggressive, destructive disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Still de Início Tardio
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Semin Arthritis Rheum
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Israel