Serotonergic terminals express a growth associated protein (GAP-43) in the adult rat spinal cord.
Neurosci Lett
; 167(1-2): 67-72, 1994 Feb 14.
Article
em En
| MEDLINE
| ID: mdl-8177531
ABSTRACT
Dual colour immunofluorescence has been used to compare the distribution of serotonin (5-hydroxytryptamine, 5-HT) and GAP-43 in the adult rat. GAP-43 immunostaining was observed in all spinal cord regions containing 5-HT immunoreactivity. 5-HT and GAP-43 double labelled fibres and varicosities were present and were most evident around motoneurones, in lamina X, and in the intermediolateral cell column. Single labelled GAP-43 fibres and varicosities were also observed and were the dominant population in the dorsal horn and in certain fibre tracts. We conclude that the 5-HT system is one of a small number of spinal cord systems that express high levels of GAP-43 in the adult.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medula Espinal
/
Glicoproteínas de Membrana
/
Serotonina
/
Terminações Nervosas
/
Proteínas do Tecido Nervoso
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Reino Unido
País de publicação:
IE
/
IRELAND
/
IRLANDA