Detection of simultaneous self-administration of testosterone and epitestosterone in healthy men.
Clin Chem
; 40(1): 106-9, 1994 Jan.
Article
em En
| MEDLINE
| ID: mdl-8287515
ABSTRACT
Combined self-administration of testosterone (T) and epitestosterone (ET) by athletes counteracts the efficiency of the corresponding urinary glucuronides (G) ratio, (T/ET)G, as an indicator of T abuse. I therefore propose 5-androstene-3 beta, 17 alpha-diol (5A3 beta 17 alpha), the immediate metabolic precursor of ET, as a new reference compound for the expression of relative excretions of T and ET. Thus (T/5A3 beta 17 alpha)G and (ET/5A3 beta 17 alpha)G become potential criteria to indicate joint administration of T and ET, since their respective threshold values (2.5 and 1.5) are exceeded even when (T/ET)G remains below the critical value of 6.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esportes
/
Testosterona
/
Detecção do Abuso de Substâncias
/
Epitestosterona
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Clin Chem
Assunto da revista:
QUIMICA CLINICA
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
França