Antibodies to neutrophil cytoplasmic antigens in rheumatoid arthritis.
Adv Exp Med Biol
; 336: 367-70, 1993.
Article
em En
| MEDLINE
| ID: mdl-8296637
ABSTRACT
In this study we examined the sera from 42 randomly selected patients with RA. ANCA was demonstrated by indirect immunofluorescence on human granulocytes in 10 patients with active disease and in none of the patients with inactive disease. ELISA's for the detection of specific antigens showed the presence of anti-myeloperoxidase in 3 patients, and anti-lactoferrin in 1 patient. The specificity of the remaining antibodies was unidentified. All 3 patients with antibodies to myeloperoxidase had vasculitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Autoanticorpos
Limite:
Humans
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Reino Unido