[Deficiencies of physiological coagulation inhibitors in children with venous thromboses of the lower limbs. Prospective study of 6 cases]. / Déficts des inhibiteurs physiologiques de la coagulation dans les thromboses veineuses des membres inférieurs de l'enfant. Etude prospective de six cas.
Ann Pediatr (Paris)
; 40(6): 348-52, 1993 Jun.
Article
em Fr
| MEDLINE
| ID: mdl-8352495
ABSTRACT
Six patients aged 3 to 14 years with lower limb vein thrombosis were included in a prospective study of deficiencies in physiological coagulation inhibitors. The laboratory evaluation included standard hemostasis tests, tests for circulating anticoagulants, immunological and functional assays of protein C, protein S, and antithrombin III, and a study of fibrinolysis. A qualitative protein S deficiency with decreased fibrinolysis and protein C deficiency were found. The family study detected asymptomatic heterozygotes in both families investigated. No antithrombin III deficiency or circulating anticoagulants were found.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tromboflebite
/
Transtornos da Coagulação Sanguínea
/
Deficiência de Proteína S
/
Deficiência de Proteína C
Tipo de estudo:
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Ann Pediatr (Paris)
Ano de publicação:
1993
Tipo de documento:
Article