Regional distributions of beta-thalassemia mutations in Turkey.
Int J Hematol
; 57(3): 207-11, 1993 Jun.
Article
em En
| MEDLINE
| ID: mdl-8364184
ABSTRACT
The distributions of twelve beta-thalassemic mutations in samples (n = 139 chromosomal samples) from four regions of Turkey were determined. The frequencies of these mutations did not reveal a notable region specific heterogeneity. In particular, the four mutations, IVS.1/nt.110(G/A), IVS.1/nt.6(T/C), IVS.1/nt.1(G/A) and nonsense codon.39(C/T), with country-scale frequencies of 35.9%, 21.6%, 13.0% and 7.2%, respectively, were found to be distributed with rather similar frequencies also on a regional scale.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talassemia beta
/
Mutação
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Int J Hematol
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Turquia