[Perioperative clinical pathomorphologic evaluation of pararectal lymph node status and its contribution to definitive decision for local excision of rectal cancer]. / Perioperative klinisch-pathomorphologische Beurteilung des pararektalen Lymphknotenstatus und ihr Beitrag zur definitiven Entscheidung für eine lokale Exstirpation des Rektumkarzinoms.

ABSTRACT

On the basis of 669 patients with rectal carcinoma, who underwent radical surgery, we evaluated by means of discriminant statistics the prognostic value of 7 factors concerning lymph node involvement. By stratifying for important prognostic factors (level of differentiation, lymphocytic stromal reaction, depth of tumour infiltration) we have revealed 3 different groups I--no or rare lymph node metastases; II--more frequent metastases but confined to "N1", and III--numerous distant metastases classified as "N2-3". On the basis of these results the final decision for local extirpation of the tumour with curative intention is made easier.