Cisplatin-resistant metastatic hepatoblastoma: complete response to carboplatin, etoposide, and liver transplantation.
Med Pediatr Oncol
; 21(7): 517-20, 1993.
Article
em En
| MEDLINE
| ID: mdl-8393511
ABSTRACT
A child with stage 4 hepatoblastoma failed to respond to treatment with cisplatin and adriamycin. She then showed a response to carboplatin with complete clearing of pulmonary metastases. Bilobar liver disease persisted, although significantly reduced in size. A liver transplant was subsequently performed and she remains in complete remission 36 months later. After the first course of carboplatin, there was a dramatic rise in alpha-feto protein which then fell exponentially. Carboplatin warrants further study in hepatoblastoma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
/
Transplante de Fígado
/
Cisplatino
/
Carcinoma Hepatocelular
/
Neoplasias Hepáticas
Limite:
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Med Pediatr Oncol
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Reino Unido