Glycogenosis type V (McArdle's disease) with hyperuricemia. A case report and clinical investigation.
Eur Neurol
; 33(3): 204-7, 1993.
Article
em En
| MEDLINE
| ID: mdl-8467838
ABSTRACT
A 28-year-old male with glycogenosis type V associated with continuous hyperuricemia during mild daily activities is reported. An aerobic exercise test using a bicycle ergometer revealed that purine metabolites, i.e., ammonia, inosine, hypoxanthine and xanthine, were transiently increased by the exercise and that a subsequent increment in uric acid continued until the following day. The accelerated purine degradation by the muscle exercise was thus shown to be able to cause the overt hyperuricemia in a patient with glycogenosis type V. Therapeutic use of fructose for glycogenosis was disappointing due to fructose-induced hyperuricemia. A search for myogenic hyperuricemia is essential for therapeutic trials.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Úrico
/
Doença de Depósito de Glicogênio Tipo V
/
Gota
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Eur Neurol
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Japão
País de publicação:
CH
/
SUIZA
/
SUÍÇA
/
SWITZERLAND