Maturation of fiber membranes in the human eye lens. Ultrastructural and Raman microspectroscopic observations.
Ophthalmic Res
; 27 Suppl 1: 78-85, 1995.
Article
em En
| MEDLINE
| ID: mdl-8577466
ABSTRACT
Electron microscopic, freeze fracture and cholesterol cytochemical studies have revealed that the maturation of lens fibers is accompanied by considerable changes in the ultrastructure of their limiting membranes. These changes are in line with biochemical studies on the cholesterol content in the lens and support the physiological notion that upon maturation lens membranes are transformed from normal permeable to nonleaky membranes. In addition it is shown that early cortical changes involved disturbances of lens membranes. As a consequence it can be postulated that, in order to be significant, future studies on the early events leading to cataractous disturbances must be carried out using a combination of histochemical, immunohistochemical and regional biochemical approaches.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Catarata
/
Cristalino
Limite:
Humans
Idioma:
En
Revista:
Ophthalmic Res
Ano de publicação:
1995
Tipo de documento:
Article
País de publicação:
CH
/
SUIZA
/
SUÍÇA
/
SWITZERLAND