Does a local anaesthetic cream (EMLA) alleviate pain from heel-lancing in neonates?
Acta Anaesthesiol Scand
; 39(8): 1028-31, 1995 Nov.
Article
em En
| MEDLINE
| ID: mdl-8607303
ABSTRACT
EMLA cream is an effective local anaesthetic agent for venipunctures in adults and children. The aim of this double-blind, randomised, and placebo-controlled study was to evaluate the effect of EMLA when heel-lancing was performed in neonates. On their third day of life, fullterm healthy infants, who underwent testing for phenylketonuria (PKU) by heel-lancing, were consecutively included in the study. One hundred and twelve neonates were allocated to eight groups according to the application time of EMLA or placebo (10 to 120 minutes). Thus in each group seven infants received active substance and seven placebo. The response to the nociceptive stimulation was assessed by studying the occurrence of a pain cry. No analgesic effect of EMLA was found. There were no adverse effects.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dor
/
Prilocaína
/
Anestésicos Locais
/
Lidocaína
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
Acta Anaesthesiol Scand
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Suécia