Age-related alterations in the auditory brainstem responses and the compound action potentials in guinea pigs.
Laryngoscope
; 106(8): 1034-9, 1996 Aug.
Article
em En
| MEDLINE
| ID: mdl-8699896
ABSTRACT
The auditory brainstem response (ABR) and the eight nerve compound action potential (CAP) were measured using click click stimuli to investigate the age-related alteration in the auditory function in 66 guinea pigs consisting of four age groups. With advancing age, a gradual elevation of the thresholds in both the ABR and CAP was clearly seen, together with the prolonged latencies for waves I, II, III, and IV to clicks at 95 dBpeSPL in the ABR. There were some individual differences in either threshold elevation or latency prolongation of both the ABR and CAP in aged guinea pigs. These findings suggest that the effect of individual differences on degenerative aging processes of the auditory system should be considered in selected aged animals, although a significant elevation of the neural auditory threshold is clearly found with advancing age as a whole.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Limiar Auditivo
/
Nervo Vestibulococlear
/
Envelhecimento
/
Potenciais Evocados Auditivos do Tronco Encefálico
/
Audição
Limite:
Animals
Idioma:
En
Revista:
Laryngoscope
Assunto da revista:
OTORRINOLARINGOLOGIA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Japão