[Erythroblastopenia during recurrence of a thymoma associated with myasthenia gravis. Apropos of a new case]. / Eritroblastopenia en el curso de un timoma recidivante asociado a miastenia gravis: a propósito de un nuevo caso.
Sangre (Barc)
; 41(3): 249-52, 1996 Jun.
Article
em Es
| MEDLINE
| ID: mdl-8755214
ABSTRACT
A new case of thymoma, myasthenia gravis and pure red cell aplasia is presented. Pure red cell aplasia came out 10 years after the diagnosis of the two other diseases in one of several relapses of metastatic thymoma with clinical signs of myasthenia. Surgery, chemotherapy and radiotherapy besides pyridostigmine treatment were used in the clinical course of the patient. A phenotypical change of medullary T lymphocytes (CD4 to CD8) was observed at the same time of pure red cell aplasia diagnosis. A dual role of medullary CD2+ T cell lymphocytes, stimulant and suppressive, over erythroid progenitor cells (BFU-E and CFU-E) was suggested by in vitro cultures.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Timoma
/
Neoplasias do Timo
/
Subpopulações de Linfócitos T
/
Aplasia Pura de Série Vermelha
/
Miastenia Gravis
Tipo de estudo:
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
Es
Revista:
Sangre (Barc)
Ano de publicação:
1996
Tipo de documento:
Article