Von Wille-brand's disease in UK dobermanns: possible correlation of a polymorphic DNA marker with disease status.

ABSTRACT

Ninety-one dobermanns have been typed for a polymorphic microsatellite DNA marker situated within an intron of the von Willebrand factor gene and the alleles correlated with von Wille-brand's disease status. Two alleles were identified, one associated only with the normal gene and the other with both normal and disease genes.