Marked reduction of mouse peritoneal CD5+ B cells by intraperitoneal administration of lipopolysaccharide.
Infect Immun
; 65(1): 122-6, 1997 Jan.
Article
em En
| MEDLINE
| ID: mdl-8975901
ABSTRACT
Intraperitoneal administration of lipopolysaccharide to mice induced a marked reduction of CD5+ B cells in the peritoneal cavity. The reduction was not induced by intravenous, subcutaneous, or oral administration of lipopolysaccharide. The reduction continued for about 10 days after the injection, and the CD5+ B-cell count recovered to the normal state about 14 days after the injection. The reduction of peritoneal CD5+ B cells might be caused by apoptotic cell death. Injection of lipopolysaccharide did not result in production of antibody to lipopolysaccharide. On the other hand, intraperitoneal injection of heat-killed bacteria did not induce a reduction of peritoneal CD5+ B cells and elicited the definite production of antibody to lipopolysaccharide.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cavidade Peritoneal
/
Lipopolissacarídeos
/
Subpopulações de Linfócitos B
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Antígenos CD5
/
Klebsiella pneumoniae
Limite:
Animals
Idioma:
En
Revista:
Infect Immun
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Japão