[Blood levels of testosterone and its urinary excretion in women of reproductive age both neurosis-free during the climacteric period and with climacteric neuroses]. / Soderzhanie testosterona v krovi i ékskretsii ego s mochoi u zhenshchin reproduktivnogo vozrasta i v period klimakteriia bez nevroza i s klimaktericheskim nevrozom.

ABSTRACT

Blood testosterone content was studied by the radioimmunological method in 12 healthy women (5 of reproductive age, and 7 with climacteric age changes) and in 4 patients at the postmenopause suffering from climateric neurosis. Urinary excretion of testosterone glucuronide was studied by means of fluorometry in 11 healthy women (4 of reproductive age, and 7 at the climacteric) and in 6 patients at the postmenopause with climacteric neurosis. Healthy women of reproductive age displayed marked individual variations in the blood testosterone content both during the folliculin and the lutein cycle phases. The indices of urinary testosterone excretion varied in this group lees. As to healthy women with age climacteric changes and a regular cycle and those during the postmenopause--they showed marked variations both in blood testosterone content and in urinary testosterone excretion. There were no significant differences in the indices studied in healthy women of reproductive age and in healthy women with age climacteric changes. But in 8 of 11 women with climacteric neurosis blood testosterone content and urinary testosterone excretion were much greater than the upper borders of its variations in healthy women.