Serum levels of virus burden in early-stage human immunodeficiency virus type 1 disease in women.
J Infect Dis
; 175(4): 795-800, 1997 Apr.
Article
em En
| MEDLINE
| ID: mdl-9086132
ABSTRACT
The fundamental clinical, viral, and immunologic features of early-stage human immunodeficiency virus type 1 (HIV-1) disease were examined in a seroprevalent cohort of 28 men and 14 women assessed longitudinally at three equally dispersed time points over a mean of 43 months. There were no gender differences in the relative risk of developing AIDS-defining end points or death. The median serum RNA levels assessed at the three study time points were 3.3-, 4.9-, and 1.5-fold lower, respectively, in women than in men. This suggests that while serum virus load may be as powerful a correlate of disease status in women as it is in men, the absolute values of the virus levels may be different in the 2 populations. These observations may have implications for the interpretation of levels of virus burden in women for the assessment of disease progression, transmission, and treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Viremia
/
Síndrome da Imunodeficiência Adquirida
/
HIV-1
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Estados Unidos