The Arabidopsis NIM1 protein shows homology to the mammalian transcription factor inhibitor I kappa B.
Plant Cell
; 9(3): 425-39, 1997 Mar.
Article
em En
| MEDLINE
| ID: mdl-9090885
ABSTRACT
The NIM1 (for noninducible immunity) gene product is involved in the signal transduction cascade leading to both systemic acquired resistance (SAR) and gene-for-gene disease resistance in Arabidopsis. We have isolated and characterized five new alleles of nim1 that show a range of phenotypes from weakly impaired in chemically induced pathogenesis-related protein-1 gene expression and fungal resistance to very strongly blocked. We have isolated the NIM1 gene by using a map-based cloning procedure. Interestingly, the NIM1 protein shows sequence homology to the mammalian signal transduction factor I kappa B subclass alpha. NF-kappa B/I kappa B signaling pathways are implicated in disease resistance responses in a range of organisms from Drosophila to mammals, suggesting that the SAR signaling pathway in plants is representative of an ancient and ubiquitous defense mechanism in higher organisms.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Plantas
/
Proteínas Proto-Oncogênicas
/
Arabidopsis
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Proteínas de Arabidopsis
/
Proteínas de Ligação a DNA
/
Mutação
Limite:
Animals
Idioma:
En
Revista:
Plant Cell
Assunto da revista:
BOTANICA
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Estados Unidos