Embryotoxicity/teratogenicity study with isomaltulose (Palatinose) in rats.
Food Chem Toxicol
; 35(3-4): 309-14, 1997.
Article
em En
| MEDLINE
| ID: mdl-9207892
ABSTRACT
The embryotoxicity/teratogenicity of the natural sweetener isomaltulose (Palatinose) was studied in Wistar rats. Groups of 24 mated females were fed diets containing isomaltulose at levels of 0, 2.5, 5 and 10% from day 0 to day 21 of pregnancy. The dams were killed on day 21 of pregnancy. No maternal toxicity occurred and no effects on reproductive performance, nor on embryonic or foetal development, including visceral and skeletal examination, were seen in any of the groups fed isomaltulose. The dietary level of 10% isomaltulose was equivalent to about 7 g/kg body weight/day.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Teratogênicos
/
Anormalidades Induzidas por Medicamentos
/
Embrião de Mamíferos
/
Desenvolvimento Embrionário e Fetal
/
Isomaltose
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Food Chem Toxicol
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Holanda