FDG hypermetabolism associated with inflammatory necrotic changes following radiation of meningioma.
J Nucl Med
; 38(7): 1027-9, 1997 Jul.
Article
em En
| MEDLINE
| ID: mdl-9225785
ABSTRACT
PET with 18F-fluoro-2-deoxy-D-glucose (FDG) is currently the noninvasive gold standard for distinguishing brain tumor recurrence from radiation necrosis. We present a case report that appears to contradict this doctrine. The patient had a history of atypical meningioma and was treated with surgical resection and postoperative proton-beam radiation therapy. Approximately 16 mo after completion of therapy, MRI demonstrated two new regions of enhancement, and an FDG-PET study was performed to further characterize these lesions. FDG-PET demonstrated an area of intense hypermetabolism, and wide surgical resection was performed. Histological examination of the surgical specimen revealed reactive changes and areas of necrosis. There was no evidence of either recurrent or radiation-induced tumor.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lesões por Radiação
/
Encéfalo
/
Neoplasias Encefálicas
/
Radioisótopos de Flúor
/
Tomografia Computadorizada de Emissão
/
Desoxiglucose
/
Meningioma
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
J Nucl Med
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Estados Unidos