Dynamic T1 measurement using snapshot-FLASH MRI.
J Magn Reson
; 127(1): 65-72, 1997 Jul.
Article
em En
| MEDLINE
| ID: mdl-9245631
ABSTRACT
The application of an inversion-recovery snapshot FLASH (fast low-angled shot) imaging sequence to the dynamic measurement of monoexponential T1 relaxation was investigated. The effect of (a) a reduction in the overall sequence repetition time, and (b) an increase of the read-pulse flip angle, on the measurement of T1 was analyzed. The error in T1 introduced by these factors is calculated, and a fuller analysis that takes them into account is presented. Data from a phantom are used to confirm this analysis. The magnitude of the errors is illustrated by measuring myocardial T1 in patients with acute ischaemic heart disease during the injection of a bolus of the contrast medium gadobenate dimeglumine. Overall, there was a 10% difference between the T1 values when the approximate and exact solutions were used; this was statistically significant. However, the difference was on average 25% for patients with a high heart rate (because of the shorter sequence-repetition time) in areas of infarcted myocardium (because of the longer T1).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Magn Reson
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Reino Unido