[Changes in the cytokine concentration during immunotherapy of superficial bladder tumors]. / Vizelet cytokinek koncentrációjának változása felületes hólyagdaganatok immunterápiája során.
Orv Hetil
; 139(2): 67-9, 1998 Jan 11.
Article
em Hu
| MEDLINE
| ID: mdl-9451905
ABSTRACT
A growing number of data support the importance of urinary cytokines in the BCG immunotherapy of superficial bladder tumours. To investigate kinetics and stability, urinary levels of IL-8, IL-2 and IL-6 cytokines after BCG treatment, were determined. Significant elevation in the level of IL-8 was established immediately following the first BCG instillation and it reached its highest value 4-6 hours after the treatment. During the first three weeks of the treatment and follow-up period IL-8 peaked significantly earlier than IL-2 or IL-6. Its early appearance associated with high stability makes IL-8 a good candidate for being considered as an effective agent with high predictive value in BCG immunotherapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
/
Vacina BCG
/
Carcinoma in Situ
/
Citocinas
Limite:
Humans
Idioma:
Hu
Revista:
Orv Hetil
Ano de publicação:
1998
Tipo de documento:
Article