The challenge and importance of defining critical limb ischemia.
Vasc Med
; 2(2): 126-31, 1997.
Article
em En
| MEDLINE
| ID: mdl-9546954
Patients with critical limb ischemia are at risk of limb loss and have very high cardiovascular and total mortality rates, which are greater than can be accounted for by the usual risk factors for atherosclerosis. A definition of critical ischemia is necessary to determine the natural history of the disease and to assess and compare the efficacy of various forms of therapy. The definition needs to be based on hemodynamic criteria because clinical manifestations and outcomes are not reliable. The reasons for the difficulties in arriving at a generally acceptable definition are explored. Building on the previous work of others, modified hemodynamic definitions for critical and subcritical ischemia, which include measurements of pressures and of indices of microcirculation, are proposed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemodinâmica
/
Isquemia
/
Perna (Membro)
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Vasc Med
Assunto da revista:
ANGIOLOGIA
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Canadá
País de publicação:
Reino Unido