How do kinases transfer phosphoryl groups?
Structure
; 6(4): 413-9, 1998 Apr 15.
Article
em En
| MEDLINE
| ID: mdl-9562560
ABSTRACT
Understanding how phosphoryl transfer is accomplished by kinases, a ubiquitous group of enzymes, is central to many biochemical processes. Qualitative analysis of the crystal structures of enzyme-substrate complexes of kinases reveals structural features of these enzymes important to phosphoryl transfer. Recently determined crystal structures which mimic the transition state complex have added new insight into the debate as to whether kinases use associative or dissociative mechanisms of catalysis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfatos
/
Fosfotransferases
Tipo de estudo:
Qualitative_research
Idioma:
En
Revista:
Structure
Assunto da revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
/
BIOTECNOLOGIA
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Canadá