Detection of bovine viral diarrhea virus in the ovaries of cattle acutely infected with bovine viral diarrhea virus.
J Vet Diagn Invest
; 10(2): 125-9, 1998 Apr.
Article
em En
| MEDLINE
| ID: mdl-9576337
ABSTRACT
Bovine viral diarrhea virus (BVDV) is recognized worldwide as a major cause of economic loss in cattle. Infection with BVDV can result in several clinical outcomes. However, the reproductive consequences may be the most important. Infertility, early embryonic death, abortion, and congenital anomalies have all been reported following acute infection with BVDV. The cause of infertility following acute BVDV infection is not known. BVDV has been isolated from the bovine ovary and has been associated with chronic oophoritis. The purpose of this study was to identify the ovarian cell types infected with BVDV following acute infection. Twelve heifers were acutely infected with noncytopathic BVDV, and ovariectomies were performed between 4 and 60 days postinfection. BVDV was isolated on days 6 and 8 postinfection. Viral antigen was detected in macrophage-like cells and stromal cells in the ovarian cortex and oophoritis was evident from 6 to 60 days postinfection. These findings indicate that acute infection with BVDV may result in changes in ovarian function that could lead to reduced fertility.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ovário
/
Doença das Mucosas por Vírus da Diarreia Viral Bovina
/
Pestivirus
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
J Vet Diagn Invest
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Estados Unidos