Purines and pyrimidines determination in urine using high-performance liquid chromatography.
Adv Exp Med Biol
; 431: 843-8, 1998.
Article
em En
| MEDLINE
| ID: mdl-9598182
ABSTRACT
Single purine and pyrimidine bases are involved in two fundamental metabolic pathways that lead to formation of the building stones of DNA and RNA. Purine and pyrimidine nucleotides are also critically important metabolites in many cellular functions. The main breakdown of purines and pyrimidines produces uric acid and B-minoacids, respectively. Therefore, the study of purine and pyrimidine compounds in body fluid has high clinical relevance. We report, in this work, our experience in purines and pyrimidines determination in urine from children presenting with a clinical picture suggesting an inborn these pathways.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Erros Inatos do Metabolismo da Purina-Pirimidina
/
Purinas
/
Pirimidinas
Limite:
Child
/
Humans
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Itália