[Brain monoamine oxidases in rats selected for their predisposition to pendular-like movements of the head and shoulder girdle]. / Monoaminoksidazy mozga krys, selektsionirovannykh na predraspolozhenie k maiatnikoobraznym dvizheniiam golovy i plechevogo poiasa.

ABSTRACT

Brain MAO activity was studied in male rats from the strains bred from Wistar stock for predisposition to pendulum movements (PM+) and for the absence of such predisposition (PM-). By 16.00 o'clock, in PM+ rats MAO A activity significantly increased in the brain hemispheres and decreased in the brainstem. By this time, MAO B/MAO A ratio decreased in the hemispheres and increased in the brainstem. Emotional (immobilization) stress induced an increase in activity both of MAO A and MAO B in the brainstem of PM+ rats and increase only in MAO A activity in the hemispheres of PM- rats. Actinomycin D abolished the effect of stress on MAO A and MAO B in PM+ rats but increased MAO A activity in the hemispheres of PM- rats. Possible molecular modifications are discussed in regulation of MAO activity in PM+ rats.