Stress hormonal factors, fatigue, and antioxidant responses to prolonged speed driving.
Pharmacol Biochem Behav
; 60(3): 747-51, 1998 Jul.
Article
em En
| MEDLINE
| ID: mdl-9678660
ABSTRACT
Oxygen free radicals have been implicated in exercise-induced cell and tissue injury, indicating an oxidative stress. Fatigue accompanied by a number of physiological and metabolic changes is in indication of overtraining. This study aimed to examine the influence of a continuous 24-h intermittent speed driving (1 h driving/1 h stop), on the response of hormones, antioxidative factors, lipid, and enzyme levels. Seven race car drivers of national level were examined before, during, and immediately after the trial of speed driving on a test designed to check endurance to stress. The parameters measured were testosterone (Tes), cortisol (Cor), IgM, IgA, cholesterol, HDL, billirubin, ceruloplasmin, urea, uric acid, creatine kinase, and transaminases. Stress hormone Cor declined significantly (p < 0.05), while Tes did not change significantly. Fatigue enzyme, aspartate transaminase (GOT) increased significantly (p < 0.05), while alanine transaminase (GPT) did not change and urea declined. Muscle enzyme, creatine kinase (CK) increased to sixfold (p < 0.01). IgA, IgM and lipids did not change. The primary antioxidant ceruloplasmin increased significantly (p < 0.001), while antioxidants uric acid and glucose remained unchanged. Among the factors measured, ceruloplasmin, cortisol, urea, GOT, and CK seem to give a picture of the organism's alertness and defence capabilities in conditions of stress and fatigue.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Condução de Veículo
/
Estresse Psicológico
/
Fadiga Mental
/
Hormônios
/
Antioxidantes
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Pharmacol Biochem Behav
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Grécia