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[The estimation of the level of mutations at the glycophorin A locus in subjects exposed to the chronic action of ionizing radiation]. / Otsenka urovnia mutatsii v lokuse glikoforina A u lits, podvergavshikhsia khronicheskomu vozdeistviiu ioniziruiushchei radiatsii.
Rozhdestvenskii, L M; Okladnikova, N D; Smirnova, T N; Tel'nov, V I; Pleshanov, P G; Kato, P; Langlois, R G.
Afiliação
  • Rozhdestvenskii LM; State Research Center of Russia, Institute of Biophysics, Moscow. rozhd@glas.apc.org
Radiats Biol Radioecol ; 38(3): 443-50, 1998.
Article em Ru | MEDLINE | ID: mdl-9682741
11 persons, who had been irradiated chronically at low dose rate under occupational conditions in 1950s in doses 220-581 cGy according data of individual film dosimeters, and 5 control persons were examined regarding the level of glycophorin A (GPA) mutation type NO and NN in blood erythrocytes. Significantly higher level of GPA mutations type NO was registered in average in the group of exposed persons (23.2 +/- 4.6 x 10(-6)) compared with the control group (10.2 +/- 2.1 x 10(-6)) through the dose dependence was expressed slightly. The coefficient of the linear regression has equaled (2.3 +/- 1.2 x 10(-6)) Gy. The outlook on GPA assay usage in retrospective biodosimetry is discussed.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Glicoforinas / Mutação / Doenças Profissionais Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: Ru Revista: Radiats Biol Radioecol Assunto da revista: GENETICA / MEDICINA NUCLEAR Ano de publicação: 1998 Tipo de documento: Article País de publicação: Federação Russa
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Glicoforinas / Mutação / Doenças Profissionais Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: Ru Revista: Radiats Biol Radioecol Assunto da revista: GENETICA / MEDICINA NUCLEAR Ano de publicação: 1998 Tipo de documento: Article País de publicação: Federação Russa