[The estimation of the level of mutations at the glycophorin A locus in subjects exposed to the chronic action of ionizing radiation]. / Otsenka urovnia mutatsii v lokuse glikoforina A u lits, podvergavshikhsia khronicheskomu vozdeistviiu ioniziruiushchei radiatsii.
Radiats Biol Radioecol
; 38(3): 443-50, 1998.
Article
em Ru
| MEDLINE
| ID: mdl-9682741
11 persons, who had been irradiated chronically at low dose rate under occupational conditions in 1950s in doses 220-581 cGy according data of individual film dosimeters, and 5 control persons were examined regarding the level of glycophorin A (GPA) mutation type NO and NN in blood erythrocytes. Significantly higher level of GPA mutations type NO was registered in average in the group of exposed persons (23.2 +/- 4.6 x 10(-6)) compared with the control group (10.2 +/- 2.1 x 10(-6)) through the dose dependence was expressed slightly. The coefficient of the linear regression has equaled (2.3 +/- 1.2 x 10(-6)) Gy. The outlook on GPA assay usage in retrospective biodosimetry is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lesões por Radiação
/
Glicoforinas
/
Mutação
/
Doenças Profissionais
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Radiats Biol Radioecol
Assunto da revista:
GENETICA
/
MEDICINA NUCLEAR
Ano de publicação:
1998
Tipo de documento:
Article
País de publicação:
Federação Russa