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[Monoclonal antibodies which recognize herpes simplex virus and their possible diagnostic application]. / Anticuerpos monoclonales (AcM) que reconocen el virus herpes simple (HSV) y su posible aplicación al diagnóstico.
Pupo Antúnez, M; Hermida Díaz, C; Morier Díaz, L; García Infante, S; Resik Aguirre, S.
Afiliação
  • Pupo Antúnez M; Instituto de Medicina Tropical Pedro Kourí, Ciudad de La Habana, Cuba.
Rev Cubana Med Trop ; 49(3): 181-5, 1997.
Article em Es | MEDLINE | ID: mdl-9685985
It is reported the obtention of monoclonal antibodies, which are capable of recognizing HSV-1 and HSV-2 viruses, by the conventional technology of cellular fusion. The monoclonal antibodies of highest positivity according to the indirect immunofluorescence technique were partially characterized. It was determined the neutralizing capacity of 2 of them (278-F7 and 70-G10), which were used to identify isolations of clinical specimens by indirect immunofluorescence. These monoclonal antibodies recognized HSV-1 up to a dilution of 1:2 560.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Simplexvirus / Herpes Simples / Anticorpos Antivirais Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: Es Revista: Rev Cubana Med Trop Ano de publicação: 1997 Tipo de documento: Article País de afiliação: Cuba País de publicação: Cuba
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Simplexvirus / Herpes Simples / Anticorpos Antivirais Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: Es Revista: Rev Cubana Med Trop Ano de publicação: 1997 Tipo de documento: Article País de afiliação: Cuba País de publicação: Cuba