Effects of capsaicin and capsaicin desensitization on alanine accumulation in rat hemidiaphragms.
Gen Pharmacol
; 31(1): 121-3, 1998 Jul.
Article
em En
| MEDLINE
| ID: mdl-9696634
ABSTRACT
1. Alanine accumulation in rat hemidiaphragms is significantly inhibited by capsaicin in a dose-dependent pattern that produced maximal effect at 1 mM. 2. The inhibitory effect of capsaicin on alanine accumulation by rat hemidiaphragms was enhanced upon preincubation with 5 mM ouabain. However, preincubation with 1 mM Verapamil did not alter the inhibitory effect of capsaicin. 3. Chemical ablation of the capsaicin-sensitive primary afferent fibers abolished the inhibitory effect of capsaicin on alanine accumulation in the rat hemidiaphragms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Diafragma
/
Capsaicina
/
Alanina
Limite:
Animals
Idioma:
En
Revista:
Gen Pharmacol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Líbano