Whipple's operation for carcinoma of the pancreatic head and the ampullary region. Short-and long-term results.
Scand J Gastroenterol
; 33(7): 759-64, 1998 Jul.
Article
em En
| MEDLINE
| ID: mdl-9712242
ABSTRACT
BACKGROUND AND METHODS:
In this retrospective review short- and long-term perspectives have been evaluated for 108 patients who, during 1982 through 1992, had Whipple's operation performed for carcinoma of the pancreatic head (PC, n=63) or the ampullary region (AC, n=45). In 24 patients the operation was not radical (21 with PC and 3 with AC).RESULTS:
Total perioperative morbidity was 60%, and 13 patients (12%) died within 30 days of operation. This decreased from 15.2% in the first half of the study period to 8.2% in the second half. Recurrence occurred in 56.2% of the remaining 73 patients, with no significant differences between PC and AC. Recurrence was related to regional lymph node metastases and poor tumour differentiation. Overall 5-year survival was 7.4% for PC and 24.8% for AC. For patients with radically excised tumours surviving 30 days the 5-year survival rates were 13.1% for PC and 30% for AC.CONCLUSION:
Careful preoperative evaluation is still of great importance.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pancreatectomia
/
Neoplasias Pancreáticas
/
Ampola Hepatopancreática
/
Adenocarcinoma
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Scand J Gastroenterol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Dinamarca