The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals.
Trends Biotechnol
; 16(8): 343-9, 1998 Aug.
Article
em En
| MEDLINE
| ID: mdl-9720323
ABSTRACT
The desire to deliver protein and peptide biopharmaceuticals conveniently and effectively has led to intense investigation of site-specific drug-delivery systems. Despite challenges, progress towards the convenient noninvasive delivery of proteins and peptides has been achieved through specific routes of administration. In addition, the delivery of proteins and peptides to specific sites of action has been utilized to lower the total delivered dose, to gain access to specific organs or body compartments and to concentrate a therapeutic dose at a specific site of pharmacological action.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Biotecnologia
/
Proteínas
/
Sistemas de Liberação de Medicamentos
Limite:
Humans
Idioma:
En
Revista:
Trends Biotechnol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Estados Unidos