Characterization of thiamine pyrophosphatase positive phagocytic cells in the neural lobe of rat pituitary.
Folia Neuropathol
; 36(2): 109-16, 1998.
Article
em En
| MEDLINE
| ID: mdl-9757622
ABSTRACT
Here, using a histochemical staining for a microglia/phagocyte marker TPP-ase (Murabe, Sano 1981), and an electron microscopy we characterized the population of pituitary phagocytic cells activated by cerebral ischemia. An intense thiamine pyrophosphatase (TPP-ase) activity was demonstrated in glial cells and some cells of blood vessels of neural lobe, late period (12 months) after experimental ischemia. TPP-ase positive cells were ultrastructurally identified as pituicytes, microglia, pericytes and perivascular cells. The product characteristic for TPP-ase activity was seen on plasma membrane of these cells. Our electron-microscopic histochemical results provide strong support for a role of pituicytes, pericytes and perivascular cells as a phagocytic cells involved in mechanism of elimination of ischemically damaged axonal endings in neural lobe.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fagócitos
/
Hipófise
/
Tiamina Pirofosfatase
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Folia Neuropathol
Assunto da revista:
NEUROLOGIA
/
PATOLOGIA
Ano de publicação:
1998
Tipo de documento:
Article