Nitric oxide production in vervet monkeys (Cercopithecus aethiops) infected with Trypanosoma brucei.
Parasite Immunol
; 20(8): 395-7, 1998 Aug.
Article
em En
| MEDLINE
| ID: mdl-9767605
ABSTRACT
A retrospective study of nitrate concentration in serum and cerebrospinal fluid (CSF) from vervet monkeys (Cercopithecus aethiops) infected with Trypanosoma brucei was undertaken. Serum nitrate was significantly elevated in parasitaemic animals. CSF nitrate detection correlated with the presence of parasites in the CNS. The results provide evidence for the production of nitric oxide (NO) in response to infection in a primate model of human African trypanosomiasis and provide the basis for the use of such a model in studies of the immunopathological effects of NO in human trypanosomiasis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trypanosoma brucei brucei
/
Tripanossomíase Africana
/
Óxido Nítrico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Parasite Immunol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Reino Unido