Sensitization to mite allergens and acute asthma in a tropical environment.
J Investig Allergol Clin Immunol
; 8(5): 281-4, 1998.
Article
em En
| MEDLINE
| ID: mdl-9827423
ABSTRACT
The objective of this study was to determine whether sensitization to certain aeroallergens is associated with acute asthma in Cartagena, Colombia. Ninety-nine subjects with acute asthma and 100 controls evaluated for other reasons were studied at a local emergency room. Sensitization was established by specific IgE determinations. Statistically significant differences between asthmatic subjects and controls were found in the prevalence of specific IgE to Dermatophagoides pteronyssinus, 64.6% vs. 28% (p = 0.0001); to Dermatophagoides farinae, 74.7% vs. 40% (p = 0.0001); to Euroglyphus maynei, 68.7% vs. 22% (p = 0.0001); and to Blomia tropicalis, 54.5% vs. 17% (p = 0.0001). The odds ratios were 4.9; 4.4; 7.7 and 5.8, respectively. In contrast, there was no significant difference between subjects with asthma and controls in the prevalence of specific IgE to Alternaria tenuis 4% vs. 1% (p = 0.35); to Paspalum notatum (Bahia grass) 28% vs. 19% (p = 0.16); to Periplaneta americana (American cockroach) 21% vs. 19% (p = 0.83); to Ambrosia artemisifolia (short ragweed) 12% vs. 23% (p = 0.11); and to cat epithelium 5% vs. 1% (p = 0.17). The results suggest that sensitization to domestic mites in subjects who reside in this tropical city is associated with acute asthma that requires emergency room treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Alérgenos
/
Ácaros
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do sul
/
Colombia
Idioma:
En
Revista:
J Investig Allergol Clin Immunol
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Colômbia