Chromosomal localization and genomic organization of the human retinal rod Na-Ca+K exchanger.
Hum Genet
; 103(4): 411-4, 1998 Oct.
Article
em En
| MEDLINE
| ID: mdl-9856482
ABSTRACT
The retinal rod Na-Ca+K exchanger is a unique calcium extrusion protein found only in the outer segments of retinal rod photoreceptors. Rod Na-Ca+K exchanger cDNA (NCKX1) has been cloned from bovine and human retinas. Here, we have used fluorescent in situ hybridization and radiation hybrid mapping to localize the human NCKX1 gene to chromosome 15q22. We have determined the genomic organization of human rod NCKX1 and found one intron in the 5' untranslated region and eight introns within the coding region.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos Par 15
/
Proteínas de Transporte
/
Trocador de Sódio e Cálcio
Limite:
Humans
Idioma:
En
Revista:
Hum Genet
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Canadá