Free and total triiodothyronine and thyroxine in malnourished Jamaican infants. The effect of diet on plasma levels of thyroid hormones, insulin and glucose during recovery
Hum Nutr Clin Nutr
; 39C: 245-57, 1985.
Artigo
em Inglês
| MedCarib
| ID: med-12066
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
Plasma concentrations of free triiodothyronine (FT3), total triiodothyronine (TT3) and total thyroxine (TT4) were reduced to 63.0, 37.7, 61.7 per cent of controls respectively in protein-energy malnutrition (PEM), while free thyroxine (FT4) was elevated by 23 per cent. There was a gradual increase of both TT4 and TT3 during recovery. The ratio of free to bound hormones was high in malnutrition and declined with recovery, indicating a deficiency of thyroid-hormone binding in malnutrition. The observation of a significant reduction (P<0.05) in T3/T4 ratios, which occurred in malnutrition and was induced during recovery after 3 d on a low energy maintenance diet, suggested depressed conversion of T4 to T3 due to energy restriction. Energy restriction also significantly (P<0.001) depressed plasma insulin concentrations in the presence of nearly constant glucose levels. (AU)
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Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Tiroxina
/
Tri-Iodotironina
/
Glicemia
/
Desnutrição Proteico-Calórica
/
Insulina
Limite:
Criança, pré-escolar
/
Humanos
/
Lactente
País/Região como assunto:
Caribe Inglês
/
Jamaica
Idioma:
Inglês
Revista:
Hum Nutr Clin Nutr
Ano de publicação:
1985
Tipo de documento:
Artigo