Endoscopic and gastric acid studies in homozygous sickle cell disease and upper abdominal pain
Gut
; 30(5): 569-72, 1989.
Article
em En
| MedCarib
| ID: med-12080
Biblioteca responsável:
JM3.1
Localização: JM3.1; RC799.G8
ABSTRACT
Upper endoscopic and gastric acid output studies were done in 51 patients with homozygous sickle cell (SS) disease and recurrent epigastric pain. Twenty (39 percent) had abnormalities in the upper gastrointestinal tract including 18 (35 percent) with peptic ulcers. Mean bassal and maximum acid output were similar in patients with and without duodenal ulcer (DU). Because DU in SS disease does not appear to be associated with high acid outputs observed in other populations, it may reflect reduced mucosal resistance, possibly resulting from ischaemia. This hypothesis was supported by the significantly lower fetal haemoglobin level among SS-DU patients. (Summary)
Buscar no Google
Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Dor
/
Úlcera Péptica
/
Abdome
/
Ácido Gástrico
/
Anemia Falciforme
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Gut
Ano de publicação:
1989
Tipo de documento:
Article