Role of splenectomy in homozygous sickle cell disease in childhood
Lancet
; 1(8368): 88-91, Jan. 14, 1984.
Artigo
em Inglês
| MedCarib
| ID: med-12148
Biblioteca responsável:
JM3.1
Localização: JM3.1; R31.L3
ABSTRACT
60 Jamaican children with homozygous sickle cell (SS) disease underwent splenectomy, 14 for prophylaxis against recurrent acute splenic sequestration and 46 for treatment of sustained hypersplenism. Age at operation varied from 9 months to 27 years (median 6 years), with a total of 369 years of patient-observation. None of the 3 patients who died, at ages 2«, 6«, and 21 years, had received prophylaxis against infection. Overwhelming sepsis was possible but not confirmed in the first two deaths which occurred 11 months and 2« years after operation; the third died from chronic renal failure 11 years after splenectomy. After operation, there were no confirmed cases of pneumococcal septicaemia or meningitis, and the commonest clinical event was the acute chest syndrome. (Summary)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Zoonoses
Base de dados:
MedCarib
Assunto principal:
Esplenectomia
/
Infecções Bacterianas
/
Anemia Falciforme
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Lancet
Ano de publicação:
1984
Tipo de documento:
Artigo