Haematological factors associated with avascular necrosis of the femoral head in homozygous sickle cell disease
Br J Haematol
; 50(1): 29-34, Jan. 1982.
Artigo
em Inglês
| MedCarib
| ID: med-12240
Biblioteca responsável:
JM3.1
Localização: JM3.1; RB145.A1H4
ABSTRACT
The haematological indices in 50 patients with homozygous sickle cell (SS) disease and avascular necrosis of the femoral head and in 180 patients with SS disease without this complication have been compared. Avascular necrosis of the femoral head was significantly associated with high total levels and with low fetal haemoglobin levels. Low fetal haemoglobin levels are associated with increased intravascular sickling. These results suggest that both intravascular sickling and the increased viscosity associated with high haemoglobin levels are related to the development of avascular necrosis of the femoral head in SS disease. (AU)
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Base de dados:
MedCarib
Assunto principal:
Necrose da Cabeça do Fêmur
/
Anemia Falciforme
Tipo de estudo:
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Br J Haematol
Ano de publicação:
1982
Tipo de documento:
Artigo