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Small bowel morphology in British Indian and Afro Caribbean subjects: evidence of tropical enteropathy
Gut ; 32(3): 256-9, Mar. 1991.
Artigo em Inglês | MedCarib | ID: med-12546
Biblioteca responsável: JM3.1
Localização: JM3.1; RC799.G8
ABSTRACT
Distal duodenal biopsy specimens taken from 30 white, 35 Indian, and 20 Afro-Caribbean residents of West Birmingham during routine endoscopy for dyspepsia, were assessed by disecting microscopy and morphometry. Finger-shaped villi were significantly less frequent in the Indian and Afro-Caribbean subjects than in the white subjects when assessed by disecting microscopy (p<0.005), and both immigrant groups had decreased mucosal thickness (p<0.01), villous height (p<0.001), villouscrypt ratios (p<0.01) and enterocyte height (p<0.05) compared with the white group. In the Indian subjects villous height and villouscrypt ratios correlated significantly with the time since the last visit to the Indian subcontinent (p<0.005). Serum alkaline phosphatase values were significantly higher in the Indian subjects compared with the white (p<0.02), and serum globulins were increased in both the Afro-Caribbean and Indian subjects (p<0.01). There were no correlations between morphometric indices and body habitus or biochemical or haematological indices and the long term effect of the morphological changes is not clear. (AU)
Assuntos
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Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Duodeno / Enteropatias Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia / Caribe / Europa Idioma: Inglês Revista: Gut Ano de publicação: 1991 Tipo de documento: Artigo
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Coleções: Bases de dados internacionais Base de dados: MedCarib Assunto principal: Duodeno / Enteropatias Limite: Adolescente / Adulto / Idoso / Feminino / Humanos / Masculino País/Região como assunto: Ásia / Caribe / Europa Idioma: Inglês Revista: Gut Ano de publicação: 1991 Tipo de documento: Artigo
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