Cytogenetic and clinical observations on West Indian patients with primary amenorrhea
Int J Gynaecol Obstet
; 8(2): 43-50, Mar. 1970.
Artigo
em Inglês
| MedCarib
| ID: med-14657
Biblioteca responsável:
JM3.1
Localização: JM3.1; RG1.I5
ABSTRACT
Forty-seven patients with primary amenorrhea, oligomenorrhea, and secondary amenorrhea were investigated by chromosome examination, and laparotomy was performed in six. Thirty-six percent of patients with primary amenorrhea showed sex chromosomal abnormality, and two cases showed autosomal anomalities. We feel that undetected mosaicism was present in some of the sexual infantile patients with apparently normal complement; probably, several of this group have gonadal dysgenesis. No abnormality was detected in patients with virilization. However, we now believe that any patient without adrenal hyperplasia should have laparotomy and removal of abnormal gonadal tissue. Laparotomy and gonadal extirpation may be considered for patients with streak gonads without virilization. Patients with normal secondary sexual development deserve full and early investigation of the genital tract, as they may have congenital anomalities associated with normal ovaries (Summary)
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Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Sinais e Sintomas
/
Citogenética
/
Amenorreia
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
Caribe
Idioma:
Inglês
Revista:
Int J Gynaecol Obstet
Ano de publicação:
1970
Tipo de documento:
Artigo