Trials with a live attenuated rubella virus vaccine, Cendehill strain
J Hyg
; 68(3): 505-10, Sept. 1970.
Artigo
em Inglês
| MedCarib
| ID: med-14870
Biblioteca responsável:
JM3.1
Localização: JM3.1; RA421.J88
ABSTRACT
This report summarizes closed, family, and open studies conducted sequentially over a 10 month period with the Cendehill rubella virus vaccine in more than 16,000 children and adolescents. This strain of rubella was attenuated by serial propogation on primary rabbit kidney cell cultures. Inoculation of the Cendehill vaccine produced seroconversion in 97 percent of the 3589 susceptible (seronegative) vaccinated persons. There was no spread of the virus to susceptible controls living in close contact with those vaccinated. The vaccine was well tolerated. No arthritis or arthralgia occured in 860 female subjects 13-18 years of age who were included in the study. The Cendehill vaccine would appear to meet the requirements of an acceptable vaccine (Summary)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Sarampo
Base de dados:
MedCarib
Assunto principal:
Vírus da Rubéola
/
Vacinas Virais
Tipo de estudo:
Ensaio clínico controlado
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J Hyg
Ano de publicação:
1970
Tipo de documento:
Artigo